Last Modified : Thursday, 12-Jan-2012 11:25 AM

CLARENCE ONGKUDON
BSc. (Chemical Engineering), Universiti Teknologi Malaysia (UTM), Johor, Malaysia, 2002
MSc. (Bioprocess Engineering), Universiti Teknologi Malaysia (UTM), Johor, Malaysia, 2005
PhD. (Bioprocess and Biochemical Engineering), Monash University, Australia, 2011
   
Position
1. Tutor  
     
Expertise
1. Microbial fermentation science and technology  
2. Bioseparation media design and functionalization  
3. Downstream processing and biomolecule purification
 
     
Current Research Projects
1. None  
     
Current Postgraduate Students
1. None  
     
Publication
Journal
  • Clarence M. Ongkudon and Michael K. Danquah. Analysis of ZnSO4-induced lipopolysaccharides precipitation by measurement of hydrodynamic sizes and Zeta potentials. Process Biochemistry (accepted).
  • Clarence M. Ongkudon, Raelene Pickering, Diane Webster and Michael K. Danquah. Cultivation of E. coli carrying a plasmid-based Measles vaccine construct (4.2 kbp pcDNA3F) employing medium optimisation and pH-temperature induction techniques. Microbial Cell Factories, 10 (2011) 16.
  • Clarence M. Ongkudon and Michael K. Danquah. Anion exchange chromatography of 4.2 kbp plasmid based vaccine (pcDNA3F) from alkaline lysed E. coli lysate using amino functionalised polymethacrylate conical monolith. Separation and Purification Technology, 78 (2011) 303 – 310.
  • Clarence M. Ongkudon and Michael K. Danquah. Endotoxin removal and plasmid DNA recovery in various metal ion solutions. Separation Science and Technology, 46 (2011) 1280 – 1282.
  • Clarence M. Ongkudon and Michael K. Danquah. Analysis of selective metal-salt-induced endotoxin precipitation in plasmid DNA purification using improved LAL assay and central composite design. Analytical Chemistry, (2011) 391 – 397.
  • Clarence M. Ongkudon, Jenny Ho, Gareth M. Forde and Michael K. Danquah. Mitigating the Looming Vaccine Crisis: Production and Delivery of Plasmid-Based Vaccines. Critical Reviews in Biotechnology, 31 (2011) 32 – 52.
  • Clarence M. Ongkudon and Michael K. Danquah. Process optimisation for anion exchange monolithic chromatography of 4.2 kbp plasmid vaccine (pcDNA3F). Journal of Chromatography B, 878 (2010) 2719 – 2725.
  • Michael W. H. Roberts, Clarence M. Ongkudon, Gareth M. Forde and Michael K. Danquah. Versatility of polymethacrylate monoliths for chromatographic purification of biomolecules. Journal of Separation Science, 32 (2009) 2485 – 2494.
  • Ongkudon C. M., Rahman B. A., and Aziz A. A. Optimization of Critical Medium Components for the Expression of Recombinant Human Transferrin in Insect Cells Baculovirus System. Jurnal Teknologi, 45(F) (2006) 19 – 30.
Proceeding
  • Clarence M. Ongkudon and Michael K. Danquah. A novel technology for continuous isolation of large biomolecules: A study on plasmid DNA production. UMS Biotechnology Symposium IV, Kota Kinabalu, Malaysia, 1st – 3rd December 2010.
  • Clarence M. Ongkudon and Michael K. Danquah. A Novel Technology for Continuous Enzyme Free Isolation of Plasmid DNA. Bioprocessing Network conference, Melbourne, Australia, 12th – 14th October 2010.
  • Ongkudon C. M. and Danquah M. K. The performance of a triethylamine activated polymethacrylate conical monolith for plasmid vaccine purification. Victorian Infection and Immunity Network symposium, Melbourne, Australia, 2010.
  • Screening of the SF900-II SFM insect cell culture medium and recombinant baculovirus for the expression of recombinant human transferrin, 15th Malaysian Society for Molecular Biology and Biotechnology scientific meeting, Kuala Lumpur, Malaysia, 2005.
  • Preliminary studies on the optimisation of recombinant human transferrin expression in insect cells baculovirus system, National Postgraduate colloquium, Penang, Malaysia, 2004.
     
Contact
     
E-mail : clarence@ums.edu.my
Tel. : +6 088 320000 ext 8536
Fax : +6088-320993
     

Biotechnology Research Institute
Universiti Malaysia Sabah
Jalan UMS
88400 Kota Kinabalu
Sabah, MALAYSIA
©2007 Biotechnology Research Institute (BRI) UMS. All rights reserved.
Please report comments and problems to our Webmaster.